Simvastatin Inhibits Activation of NADPH Oxidase/p38 MAPK Pathway and Enhances Expression of Antioxidant Protein in Parkinson Disease Models

Evidence suggests that oxidative stress is involved in the pathogenesis of Parkinson disease (PD). Simvastatin has been suggested to protect against oxidative stress in several diseases. However, the molecular mechanisms by which simvastatin protects against neuropathology and oxidative damage in PD...

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Detalles Bibliográficos
Autores principales: Tong, Huichun, Zhang, Xiuping, Meng, Xingjun, Lu, Lingli, Mai, Dongmei, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972184/
https://www.ncbi.nlm.nih.gov/pubmed/29872377
http://dx.doi.org/10.3389/fnmol.2018.00165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972184/
https://www.ncbi.nlm.nih.gov/pubmed/29872377
http://dx.doi.org/10.3389/fnmol.2018.00165

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