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mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation
Accumulating evidence suggests that metabolic master regulators, including mTOR, regulate adaptive and innate immune responses. Resident mesenchymal tissue components are increasingly recognized as key effector cells in inflammation. Whether mTOR also controls the inflammatory response in fibroblast...
Autores principales: | Karonitsch, Thomas, Kandasamy, Richard K., Kartnig, Felix, Herdy, Barbara, Dalwigk, Karolina, Niederreiter, Birgit, Holinka, Johannes, Sevelda, Florian, Windhager, Reinhard, Bilban, Martin, Weichhart, Thomas, Säemann, Marcus, Pap, Thomas, Steiner, Günter, Smolen, Josef S., Kiener, Hans P., Superti-Furga, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972226/ https://www.ncbi.nlm.nih.gov/pubmed/29768212 http://dx.doi.org/10.1016/j.celrep.2018.04.044 |
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