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Silencing of Syntaxin 1A in the Dopaminergic Neurons Decreases the Activity of the Dopamine Transporter and Prevents Amphetamine-Induced Behaviors in C. elegans

The dopamine transporter (DAT) is a cell membrane protein whose main function is to reuptake the dopamine (DA) released in the synaptic cleft back into the dopaminergic neurons. Previous studies suggested that the activity of DAT is regulated by allosteric proteins such as Syntaxin-1A and is altered...

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Detalles Bibliográficos
Autores principales: Lanzo, Ambra, Safratowich, Bryan D., Kudumala, Sirisha R., Gallotta, Ivan, Zampi, Giuseppina, Di Schiavi, Elia, Carvelli, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972276/
https://www.ncbi.nlm.nih.gov/pubmed/29872404
http://dx.doi.org/10.3389/fphys.2018.00576

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