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Silencing of Syntaxin 1A in the Dopaminergic Neurons Decreases the Activity of the Dopamine Transporter and Prevents Amphetamine-Induced Behaviors in C. elegans
The dopamine transporter (DAT) is a cell membrane protein whose main function is to reuptake the dopamine (DA) released in the synaptic cleft back into the dopaminergic neurons. Previous studies suggested that the activity of DAT is regulated by allosteric proteins such as Syntaxin-1A and is altered...
Autores principales: | Lanzo, Ambra, Safratowich, Bryan D., Kudumala, Sirisha R., Gallotta, Ivan, Zampi, Giuseppina, Di Schiavi, Elia, Carvelli, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972276/ https://www.ncbi.nlm.nih.gov/pubmed/29872404 http://dx.doi.org/10.3389/fphys.2018.00576 |
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