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SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn’s Disease and Peripheral T Cell Reduction

In our previous study, we observed a severe reduction in the Src homology 2-containing-inositol-phosphatase-1 (SHIP1) protein in a subpopulation of subjects from a small adult Crohn’s Disease (CD) cohort. This pilot study had been undertaken since we had previously demonstrated that engineered defic...

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Detalles Bibliográficos
Autores principales:	Fernandes, Sandra, Srivastava, Neetu, Sudan, Raki, Middleton, Frank A., Shergill, Amandeep K., Ryan, James C., Kerr, William G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972310/ https://www.ncbi.nlm.nih.gov/pubmed/29872435 http://dx.doi.org/10.3389/fimmu.2018.01100

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