Cargando…

Interrogating the Functions of PRDM9 Domains in Meiosis

Homologous recombination is required for proper segregation of homologous chromosomes during meiosis. It occurs predominantly at recombination hotspots that are defined by the DNA binding specificity of the PRDM9 protein. PRDM9 contains three conserved domains typically involved in regulation of tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thibault-Sennett, Sarah, Yu, Qi, Smagulova, Fatima, Cloutier, Jeff, Brick, Kevin, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972421/ https://www.ncbi.nlm.nih.gov/pubmed/29674518 http://dx.doi.org/10.1534/genetics.118.300565

Ejemplares similares

Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility
por: Mihola, Ondrej, et al.
Publicado: (2021)

Histone methyltransferase PRDM9 is not essential for meiosis in male mice
por: Mihola, Ondrej, et al.
Publicado: (2019)

Extensive sex differences at the initiation of genetic recombination
por: Brick, Kevin, et al.
Publicado: (2018)

Genetic recombination is directed away from functional genomic elements in mice
por: Brick, Kevin, et al.
Publicado: (2012)

The evolutionary turnover of recombination hot spots contributes to speciation in mice
por: Smagulova, Fatima, et al.
Publicado: (2016)

Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles
por: Alleva, Benjamin, et al.
Publicado: (2021)

Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA
por: Khil, Pavel P., et al.
Publicado: (2012)

Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele
por: Smagulova, Fatima, et al.
Publicado: (2013)

The PRDM9 KRAB domain is required for meiosis and involved in protein interactions
por: Imai, Yukiko, et al.
Publicado: (2017)

After the break: DSB end processing in mouse meiosis
por: Brick, Kevin, et al.
Publicado: (2020)

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
por: Altemose, Nicolas, et al.
Publicado: (2017)

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
por: Davies, Benjamin, et al.
Publicado: (2016)

Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis
por: Lam, Kwan-Wood Gabriel, et al.
Publicado: (2019)

ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis
por: Paiano, Jacob, et al.
Publicado: (2020)

PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis
por: Parvanov, Emil D., et al.
Publicado: (2017)

Kinesin 6 Regulation in Drosophila Female Meiosis by the Non-conserved N- and C- Terminal Domains
por: Das, Arunika, et al.
Publicado: (2018)

The complex binding of PRDM9
por: Ségurel, Laure
Publicado: (2013)

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
por: Baker, Zachary, et al.
Publicado: (2017)

Pinpointing the PRDM9-PRDM7 Gene Duplication Event During Primate Divergence
por: Heerschop, Sacha, et al.
Publicado: (2021)

Comparison of long-read sequencing technologies in interrogating bacteria and fly genomes
por: Tvedte, Eric S, et al.
Publicado: (2021)

Trans-Lesion DNA Polymerases May Be Involved in Yeast Meiosis
por: Arbel-Eden, Ayelet, et al.
Publicado: (2013)

A Computational Approach to Developing Mathematical Models of Polyploid Meiosis
por: Rehmsmeier, Marc
Publicado: (2013)

Comparative Cytology of Female Meiosis I Among Drosophila Species
por: Majekodunmi, Ahmed, et al.
Publicado: (2020)

Rare allelic forms of PRDM9 associated with childhood leukemogenesis
por: Hussin, Julie, et al.
Publicado: (2013)

Zinc Finger Domain of the PRDM9 Gene on Chromosome 1 Exhibits High Diversity in Ruminants but Its Paralog PRDM7 Contains Multiple Disruptive Mutations
por: Ahlawat, Sonika, et al.
Publicado: (2016)

High Diversity at PRDM9 in Chimpanzees and Bonobos
por: Groeneveld, Linn Fenna, et al.
Publicado: (2012)

Characterization of Prdm9 in Equids and Sterility in Mules
por: Steiner, Cynthia C., et al.
Publicado: (2013)

Primate evolution of the recombination regulator PRDM9
por: Schwartz, Jerrod J., et al.
Publicado: (2014)

PRDM9, a driver of the genetic map
por: Grey, Corinne, et al.
Publicado: (2018)

Discovery of a chemical probe for PRDM9
por: Allali-Hassani, Abdellah, et al.
Publicado: (2019)

Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis
por: Milano, Carolyn R., et al.
Publicado: (2019)

Behavior of Aberrant Chromosome Configurations in Drosophila melanogaster Female Meiosis I
por: Gilliland, William D., et al.
Publicado: (2014)

Modulating Crossover Frequency and Interference for Obligate Crossovers in Saccharomyces cerevisiae Meiosis
por: Chakraborty, Parijat, et al.
Publicado: (2017)

Sex Chromosome Pairing Mediated by Euchromatic Homology in Drosophila Male Meiosis
por: Hylton, Christopher A., et al.
Publicado: (2020)

A molecular cell biology toolkit for the study of meiosis in the silkworm Bombyx mori
por: Xiang, Youbin, et al.
Publicado: (2023)

Extraordinary Molecular Evolution in the PRDM9 Fertility Gene
por: Thomas, James H., et al.
Publicado: (2009)

Prdm9 Polymorphism Unveils Mouse Evolutionary Tracks
por: Kono, Hiromitsu, et al.
Publicado: (2014)

Evolution of the recombination regulator PRDM9 in minke whales
por: Damm, Elena, et al.
Publicado: (2022)

Identification of nonhistone substrates of the lysine methyltransferase PRDM9
por: Hanquier, Jocelyne N., et al.
Publicado: (2023)

Nondisjunctional Segregations in Drosophila Female Meiosis I Are Preceded by Homolog Malorientation at Metaphase Arrest
por: Gillies, Shane C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3dcin19bsa2ffq5c0hg29ucbea