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Interrogating the Functions of PRDM9 Domains in Meiosis

Homologous recombination is required for proper segregation of homologous chromosomes during meiosis. It occurs predominantly at recombination hotspots that are defined by the DNA binding specificity of the PRDM9 protein. PRDM9 contains three conserved domains typically involved in regulation of tra...

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Detalles Bibliográficos
Autores principales:	Thibault-Sennett, Sarah, Yu, Qi, Smagulova, Fatima, Cloutier, Jeff, Brick, Kevin, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972421/ https://www.ncbi.nlm.nih.gov/pubmed/29674518 http://dx.doi.org/10.1534/genetics.118.300565

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