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Toppar: an interactive browser for viewing association study results

SUMMARY: Data integration and visualization help geneticists make sense of large amounts of data. To help facilitate interpretation of genetic association data we developed Toppar, a customizable visualization tool that stores results from association studies and enables browsing over multiple resul...

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Detalles Bibliográficos
Autores principales: Juliusdottir, Thorhildur, Banasik, Karina, Robertson, Neil R, Mott, Richard, McCarthy, Mark I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972658/
https://www.ncbi.nlm.nih.gov/pubmed/29325066
http://dx.doi.org/10.1093/bioinformatics/btx840
Descripción
Sumario:SUMMARY: Data integration and visualization help geneticists make sense of large amounts of data. To help facilitate interpretation of genetic association data we developed Toppar, a customizable visualization tool that stores results from association studies and enables browsing over multiple results, by combining features from existing tools and linking to appropriate external databases. AVAILABILITY AND IMPLEMENTATION: Detailed information on Toppar’s features and functionality are on our website http://mccarthy.well.ox.ac.uk/toppar/docs along with instructions on how to download, install and run Toppar. Our online version of Toppar is accessible from the website and can be test-driven using Firefox, Safari or Chrome on sub-sets of publicly available genome-wide association study anthropometric waist and body mass index data (Locke et al., 2015; Shungin et al., 2015) from the Genetic Investigation of ANthropometric Traits consortium.