Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma

Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surger...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haili, Zhan, Haiyu, Yao, Zhigang, Liu, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972752/
https://www.ncbi.nlm.nih.gov/pubmed/29951351
http://dx.doi.org/10.5414/CNCS109443
Descripción
Sumario:Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surgery, unenhanced computed tomography scans showed recurrence as well as metastasis in the abdomen and lung. The patient succumbed to rapid neoplastic progression of the disease 6 months later.

Ejemplares similares