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Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma

Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surger...

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Detalles Bibliográficos
Autores principales: Wang, Haili, Zhan, Haiyu, Yao, Zhigang, Liu, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972752/
https://www.ncbi.nlm.nih.gov/pubmed/29951351
http://dx.doi.org/10.5414/CNCS109443
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author Wang, Haili
Zhan, Haiyu
Yao, Zhigang
Liu, Qingwei
author_facet Wang, Haili
Zhan, Haiyu
Yao, Zhigang
Liu, Qingwei
author_sort Wang, Haili
collection PubMed
description Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surgery, unenhanced computed tomography scans showed recurrence as well as metastasis in the abdomen and lung. The patient succumbed to rapid neoplastic progression of the disease 6 months later.
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spelling pubmed-59727522018-06-27 Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma Wang, Haili Zhan, Haiyu Yao, Zhigang Liu, Qingwei Clin Nephrol Case Stud Case Report Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surgery, unenhanced computed tomography scans showed recurrence as well as metastasis in the abdomen and lung. The patient succumbed to rapid neoplastic progression of the disease 6 months later. Dustri-Verlag Dr. Karl Feistle 2018-05-24 /pmc/articles/PMC5972752/ /pubmed/29951351 http://dx.doi.org/10.5414/CNCS109443 Text en © Dustri-Verlag Dr. K. Feistle http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wang, Haili
Zhan, Haiyu
Yao, Zhigang
Liu, Qingwei
Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title_full Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title_fullStr Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title_full_unstemmed Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title_short Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
title_sort malignant renal epithelioid angiomyolipoma with tfe3 gene amplification mimicking renal carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972752/
https://www.ncbi.nlm.nih.gov/pubmed/29951351
http://dx.doi.org/10.5414/CNCS109443
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AT yaozhigang malignantrenalepithelioidangiomyolipomawithtfe3geneamplificationmimickingrenalcarcinoma
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