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Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma
Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surger...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dustri-Verlag Dr. Karl Feistle
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972752/ https://www.ncbi.nlm.nih.gov/pubmed/29951351 http://dx.doi.org/10.5414/CNCS109443 |
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author | Wang, Haili Zhan, Haiyu Yao, Zhigang Liu, Qingwei |
author_facet | Wang, Haili Zhan, Haiyu Yao, Zhigang Liu, Qingwei |
author_sort | Wang, Haili |
collection | PubMed |
description | Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surgery, unenhanced computed tomography scans showed recurrence as well as metastasis in the abdomen and lung. The patient succumbed to rapid neoplastic progression of the disease 6 months later. |
format | Online Article Text |
id | pubmed-5972752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Dustri-Verlag Dr. Karl Feistle |
record_format | MEDLINE/PubMed |
spelling | pubmed-59727522018-06-27 Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma Wang, Haili Zhan, Haiyu Yao, Zhigang Liu, Qingwei Clin Nephrol Case Stud Case Report Malignant renal epithelioid angiomyolipoma (EAML) is an extremely rare disease with a poor prognosis, and currently there are no uniform criteria for its biological behavior. Here, we present a case of malignant renal EAML with TFE3 gene amplification in a 53-year-old woman. Four months after surgery, unenhanced computed tomography scans showed recurrence as well as metastasis in the abdomen and lung. The patient succumbed to rapid neoplastic progression of the disease 6 months later. Dustri-Verlag Dr. Karl Feistle 2018-05-24 /pmc/articles/PMC5972752/ /pubmed/29951351 http://dx.doi.org/10.5414/CNCS109443 Text en © Dustri-Verlag Dr. K. Feistle http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Wang, Haili Zhan, Haiyu Yao, Zhigang Liu, Qingwei Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title | Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title_full | Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title_fullStr | Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title_full_unstemmed | Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title_short | Malignant renal epithelioid angiomyolipoma with TFE3 gene amplification mimicking renal carcinoma |
title_sort | malignant renal epithelioid angiomyolipoma with tfe3 gene amplification mimicking renal carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972752/ https://www.ncbi.nlm.nih.gov/pubmed/29951351 http://dx.doi.org/10.5414/CNCS109443 |
work_keys_str_mv | AT wanghaili malignantrenalepithelioidangiomyolipomawithtfe3geneamplificationmimickingrenalcarcinoma AT zhanhaiyu malignantrenalepithelioidangiomyolipomawithtfe3geneamplificationmimickingrenalcarcinoma AT yaozhigang malignantrenalepithelioidangiomyolipomawithtfe3geneamplificationmimickingrenalcarcinoma AT liuqingwei malignantrenalepithelioidangiomyolipomawithtfe3geneamplificationmimickingrenalcarcinoma |