Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line

This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Ardelt, A., Carpenter, R., Iwuchukwu, I., Zhang, A., Lin, W., Kosciuczuk, E., Hinkson, C., Rebeiz, T., Reitz, S., King, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972843/
https://www.ncbi.nlm.nih.gov/pubmed/29854897
http://dx.doi.org/10.1016/j.dib.2017.10.033
_version_ 1783326490227638272
author Ardelt, A.
Carpenter, R.
Iwuchukwu, I.
Zhang, A.
Lin, W.
Kosciuczuk, E.
Hinkson, C.
Rebeiz, T.
Reitz, S.
King, P.
author_facet Ardelt, A.
Carpenter, R.
Iwuchukwu, I.
Zhang, A.
Lin, W.
Kosciuczuk, E.
Hinkson, C.
Rebeiz, T.
Reitz, S.
King, P.
author_sort Ardelt, A.
collection PubMed
description This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented.
format Online
Article
Text
id pubmed-5972843
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-59728432018-05-31 Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line Ardelt, A. Carpenter, R. Iwuchukwu, I. Zhang, A. Lin, W. Kosciuczuk, E. Hinkson, C. Rebeiz, T. Reitz, S. King, P. Data Brief Neuroscience This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented. Elsevier 2017-10-17 /pmc/articles/PMC5972843/ /pubmed/29854897 http://dx.doi.org/10.1016/j.dib.2017.10.033 Text en © 2018 Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Neuroscience
Ardelt, A.
Carpenter, R.
Iwuchukwu, I.
Zhang, A.
Lin, W.
Kosciuczuk, E.
Hinkson, C.
Rebeiz, T.
Reitz, S.
King, P.
Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title_full Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title_fullStr Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title_full_unstemmed Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title_short Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line
title_sort characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a hur transgenic mouse line
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972843/
https://www.ncbi.nlm.nih.gov/pubmed/29854897
http://dx.doi.org/10.1016/j.dib.2017.10.033
work_keys_str_mv AT ardelta characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT carpenterr characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT iwuchukwui characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT zhanga characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT linw characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT kosciuczuke characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT hinksonc characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT rebeizt characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT reitzs characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline
AT kingp characterizationofthetransientmiddlecerebralarteryocclusionmodelofischemicstrokeinahurtransgenicmouseline

Ejemplares similares