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A strategy for L-isoleucine dioxygenase screening and 4-hydroxyisoleucine production by resting cells

L-Isoleucine dioxygenase (IDO) specifically converts L-isoleucine(L-Ile) to 4-hydroxyisoleucine(4-HIL). To obtain IDO with improved activity, a strategy was developed that is dependent on the restoration of succinate-minus E. coli cell growth by the coupling of L-Ile hydroxylation and the oxidation...

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Detalles Bibliográficos
Autores principales:	Zhang, Chenglin, Ma, Jie, Li, Zhixiang, Liang, Yunlong, Xu, Qingyang, Xie, Xixian, Chen, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972919/ https://www.ncbi.nlm.nih.gov/pubmed/28430004 http://dx.doi.org/10.1080/21655979.2017.1304872

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