Pan-negative型非小细胞肺癌的研究进展

In recent years, series of driver genes, such as EGFR, KRAS/NRAS, BRAF, PIK3CA, ALK and ROS1 and so on, have been found in non-small cell lung cancer (NSCLC) one after another with the development of molecular detecting technology. Targeted drugs bring benefits for these NSCLC patients with driver g...

Descripción completa

Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2018
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973015/
https://www.ncbi.nlm.nih.gov/pubmed/29526181
http://dx.doi.org/10.3779/j.issn.1009-3419.2018.02.07
_version_ 1783326525631758336
collection PubMed
description In recent years, series of driver genes, such as EGFR, KRAS/NRAS, BRAF, PIK3CA, ALK and ROS1 and so on, have been found in non-small cell lung cancer (NSCLC) one after another with the development of molecular detecting technology. Targeted drugs bring benefits for these NSCLC patients with driver gene variations. However, some NSCLC did not have any known driver gene variations; we called it pan-negative lung cancer. In this paper, we summarize the concept, clinical pathological characteristics, the epidemiological characteristics, treatment and prognosis of pan-negative NSCLC.
format Online
Article
Text
id pubmed-5973015
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher 中国肺癌杂志编辑部
record_format MEDLINE/PubMed
spelling pubmed-59730152018-07-06 Pan-negative型非小细胞肺癌的研究进展 Zhongguo Fei Ai Za Zhi 综述 In recent years, series of driver genes, such as EGFR, KRAS/NRAS, BRAF, PIK3CA, ALK and ROS1 and so on, have been found in non-small cell lung cancer (NSCLC) one after another with the development of molecular detecting technology. Targeted drugs bring benefits for these NSCLC patients with driver gene variations. However, some NSCLC did not have any known driver gene variations; we called it pan-negative lung cancer. In this paper, we summarize the concept, clinical pathological characteristics, the epidemiological characteristics, treatment and prognosis of pan-negative NSCLC. 中国肺癌杂志编辑部 2018-02-20 /pmc/articles/PMC5973015/ /pubmed/29526181 http://dx.doi.org/10.3779/j.issn.1009-3419.2018.02.07 Text en 版权所有©《中国肺癌杂志》编辑部2018 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/
spellingShingle 综述
Pan-negative型非小细胞肺癌的研究进展
title Pan-negative型非小细胞肺癌的研究进展
title_full Pan-negative型非小细胞肺癌的研究进展
title_fullStr Pan-negative型非小细胞肺癌的研究进展
title_full_unstemmed Pan-negative型非小细胞肺癌的研究进展
title_short Pan-negative型非小细胞肺癌的研究进展
title_sort pan-negative型非小细胞肺癌的研究进展
topic 综述
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973015/
https://www.ncbi.nlm.nih.gov/pubmed/29526181
http://dx.doi.org/10.3779/j.issn.1009-3419.2018.02.07
work_keys_str_mv AT pannegativexíngfēixiǎoxìbāofèiáideyánjiūjìnzhǎn
AT pannegativexíngfēixiǎoxìbāofèiáideyánjiūjìnzhǎn
AT pannegativexíngfēixiǎoxìbāofèiáideyánjiūjìnzhǎn

Ejemplares similares