Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement

Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred f...

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Detalles Bibliográficos
Autores principales: Lee, Kanghoon, Kim, Hyeong Ryul, Roh, Jin, Ok, You Jung, Jeon, Bo Bae, Kim, Young Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973223/
https://www.ncbi.nlm.nih.gov/pubmed/29854671
http://dx.doi.org/10.5090/kjtcs.2018.51.3.223
Descripción
Sumario:Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred for evaluation of a mediastinal mass. The patient underwent surgical excision of the tumor via video-assisted thoracoscopic surgery. Histologic examination revealed marked proliferation of atypical histiocytes with sclerosis, and the results of immunohistochemical staining were suggestive of ECD.

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