Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement

Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred f...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Kanghoon, Kim, Hyeong Ryul, Roh, Jin, Ok, You Jung, Jeon, Bo Bae, Kim, Young Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973223/
https://www.ncbi.nlm.nih.gov/pubmed/29854671
http://dx.doi.org/10.5090/kjtcs.2018.51.3.223
_version_ 1783326571497521152
author Lee, Kanghoon
Kim, Hyeong Ryul
Roh, Jin
Ok, You Jung
Jeon, Bo Bae
Kim, Young Woong
author_facet Lee, Kanghoon
Kim, Hyeong Ryul
Roh, Jin
Ok, You Jung
Jeon, Bo Bae
Kim, Young Woong
author_sort Lee, Kanghoon
collection PubMed
description Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred for evaluation of a mediastinal mass. The patient underwent surgical excision of the tumor via video-assisted thoracoscopic surgery. Histologic examination revealed marked proliferation of atypical histiocytes with sclerosis, and the results of immunohistochemical staining were suggestive of ECD.
format Online
Article
Text
id pubmed-5973223
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Korean Society for Thoracic and Cardiovascular Surgery
record_format MEDLINE/PubMed
spelling pubmed-59732232018-06-01 Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement Lee, Kanghoon Kim, Hyeong Ryul Roh, Jin Ok, You Jung Jeon, Bo Bae Kim, Young Woong Korean J Thorac Cardiovasc Surg Case Report Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred for evaluation of a mediastinal mass. The patient underwent surgical excision of the tumor via video-assisted thoracoscopic surgery. Histologic examination revealed marked proliferation of atypical histiocytes with sclerosis, and the results of immunohistochemical staining were suggestive of ECD. The Korean Society for Thoracic and Cardiovascular Surgery 2018-06 2018-06-05 /pmc/articles/PMC5973223/ /pubmed/29854671 http://dx.doi.org/10.5090/kjtcs.2018.51.3.223 Text en Copyright © 2018 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Kanghoon
Kim, Hyeong Ryul
Roh, Jin
Ok, You Jung
Jeon, Bo Bae
Kim, Young Woong
Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title_full Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title_fullStr Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title_full_unstemmed Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title_short Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement
title_sort erdheim-chester disease presenting as an anterior mediastinal tumor without skeletal involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973223/
https://www.ncbi.nlm.nih.gov/pubmed/29854671
http://dx.doi.org/10.5090/kjtcs.2018.51.3.223
work_keys_str_mv AT leekanghoon erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement
AT kimhyeongryul erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement
AT rohjin erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement
AT okyoujung erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement
AT jeonbobae erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement
AT kimyoungwoong erdheimchesterdiseasepresentingasananteriormediastinaltumorwithoutskeletalinvolvement

Ejemplares similares