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Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation
The nuclear lamina contributes to the regulation of gene expression and to chromatin organization. Mutations in A-type nuclear lamins cause laminopathies, some of which are associated with a loss of heterochromatin at the nuclear periphery. Until recently however, little if any information has been...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973257/ https://www.ncbi.nlm.nih.gov/pubmed/29517398 http://dx.doi.org/10.1080/19491034.2018.1449498 |