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Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response

Mammalian nuclei are equipped with a framework of intermediate filaments that function as a karyoskeleton. This nuclear scaffold, formed primarily by lamins (A-type and B-type), maintains the spatial and functional organization of the genome and of sub-nuclear compartments. Over the past decade, a b...

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Detalles Bibliográficos
Autores principales: Graziano, Simona, Kreienkamp, Ray, Coll-Bonfill,, Nuria, Gonzalo, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973265/
https://www.ncbi.nlm.nih.gov/pubmed/29637811
http://dx.doi.org/10.1080/19491034.2018.1454168

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