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Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet
BACKGROUND: Levodropropizine is a non-opioid antitussive agent that inhibits cough reflex by reducing the release of sensory peptide in the peripheral region. To improve patients’ compliance, a controlled-release (CR) tablet is under development. The aim of this study was to compare the pharmacokine...
Autores principales: | Lee, Soyoung, Nam, Kyu-Yeol, Oh, Jaeseong, Lee, SeungHwan, Cho, Sang-Min, Choi, Youn-Woong, Cho, Joo-Youn, Lee, Beom-Jin, Hong, Jang Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973308/ https://www.ncbi.nlm.nih.gov/pubmed/29872264 http://dx.doi.org/10.2147/DDDT.S146958 |
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