单孔与三孔胸腔镜肺部手术后急慢性疼痛的对比研究

BACKGROUND AND OBJECTIVE: Through the comparative analysis of the acute and chronic pain postoperative between the single port and triple port video-assisted thoracic surgery to seek the better method which can reduce the incidence of acute and chronic pain in patients with lung cancer. METHODS: Data of 232 patients who underwent single port -VATS (n=131) or triple port VATS (n=101) for non-small cell lung cancer (NSCLC) on January 1, 2016 to June 30, 2017 in our hospital were analyzed.The clinical and operative data were assessed, numeric rating scale (NRS) was used to evaluate the mean pain score on the 1(th), 2(th), 3(th), 7(th), 14(th) days, 3(th) months and 6(th) months postoperative. RESULTS: Both groups were similar in clinical characteristics, there were no perioperative death in two groups.In the 1(th), 2(th), 7(th), 14(th) days and 3(th), 6(th) months postoperative, the NRS score of the single port group was superior, and the difference was significant compared with the triple port (P < 0.05).There was no statistically significant difference between the two groups in operative time, blood loss, postoperative hospitalization time, duration of chest tube, the NRS scores in the 3 d (P > 0.05).Univariate and multivariate analysis of the occurrence on the chronic pain showed that the operation time, surgical procedure and the 14(th) NRS score were risk factors for chronic pain (P < 0.05). CONCLUSION: The single port thoracoscopic surgery has an advantage in the incidence of acute and chronic pain in patients with non-small cell lung cancer.Shorter operative time can reduce the occurrence of chronic pain.The 14(th) day NRS score is a risk factor for chronic pain postoperative.