肺癌术后短期中链甘油三酯饮食临床效果的前瞻性随机研究

BACKGROUND AND OBJECTIVE: It has been proven that medium chain triglyceride (MCT) diet was contribute to fast track recovery after surgery in patients with operation. In this study, the benefit of postoperative short term MCT diet support was investigated for non-small cell lung cancer patients who underwent anatomic resection. METHODS: A prospective study was planned with the approval of our institutional review board. 117 lung cancer patients who underwent anatomic resection in a single medical group between December 2015 and March 2016 were randomized. 62 patients were applied a MCT diet. and 55 patients in the control group who were fed with only normal diet, and the serum albumin levels, anus exhaust time, chest drainage, chest drainage time, the hospitalization time of post operation, average hospital cost were analysed. RESULTS: The mean anus exhaust time in MCT group [(27.87±14.38) h] was significantly shorter than that in RDG group [(45.18±8.62) h] (P < 0.001); The mean chest tube drainage time in MCT group [(75.40±48.41) h] were less than that in RDG group [(110.64±94.19) h] (P=0.025). The mean chest tube drainage volume in MCT group [395 mL] were less than that in RDG group [590 mL] (P=0.027). The hospitalization time of post operation was (5.26±2.96) d in MCT group against (6.73±3.99) d in RGD group (P=0.030). The serum albumin levels of postoperative in MCT group [(37.26±2.70) g/L)] was significantly higher than that in RDG group [(35.92±3.12) g/L)] (P=0.023). CONCLUSIONS: The results of this study demonstrated that postoperative short term MCT diet is beneficial in postoperative gastrointestinal function fast recovered and shorten the hospitalization time in non-small cell lung cancer patients after surgery.