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LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway
BACKGROUND: In the present study, we aimed to investigate the role of LGR6 in the progression of gastric cancer (GC) and explore the intrinsic molecular mechanisms. MATERIALS AND METHODS: The lentiviral LGR6 shRNA (sh-LGR6) and lentiviral expression vector of LGR6 gene (OE-LGR6) were used to regulat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973468/ https://www.ncbi.nlm.nih.gov/pubmed/29872314 http://dx.doi.org/10.2147/OTT.S149303 |