LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway

BACKGROUND: In the present study, we aimed to investigate the role of LGR6 in the progression of gastric cancer (GC) and explore the intrinsic molecular mechanisms. MATERIALS AND METHODS: The lentiviral LGR6 shRNA (sh-LGR6) and lentiviral expression vector of LGR6 gene (OE-LGR6) were used to regulat...

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Detalles Bibliográficos
Autores principales: Ke, Jing, Ma, Peng, Chen, Jinpeng, Qin, Jun, Qian, Haixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973468/
https://www.ncbi.nlm.nih.gov/pubmed/29872314
http://dx.doi.org/10.2147/OTT.S149303

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