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Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression

LInkers of Nucleoskeleton and Cytoskeleton (LINC) complexes, composed of SUN and KASH-domain proteins, span the nuclear envelope and physically connect the nuclear interior to cytoskeletal elements. Most human cells contain two SUN proteins, Sun1 and Sun2, and several KASH-proteins suggesting that m...

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Detalles Bibliográficos
Autores principales: May, Christopher K., Carroll, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973619/
https://www.ncbi.nlm.nih.gov/pubmed/29813079
http://dx.doi.org/10.1371/journal.pone.0197621