Cargando…

An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease

TL1A is an attractive therapeutic target for the treatment of mucosal inflammation associated with inflammatory bowel disease (IBD) and asthma. Blockade of the TL1A pathway has been shown to reduce inflammatory responses while leaving baseline immunity intact, and to be beneficial in animal models o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clarke, Adam W., Poulton, Lynn, Shim, Doris, Mabon, David, Butt, Danyal, Pollard, Matthew, Pande, Vanya, Husten, Jean, Lyons, Jacquelyn, Tian, Chen, Doyle, Anthony G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973687/ https://www.ncbi.nlm.nih.gov/pubmed/29436901 http://dx.doi.org/10.1080/19420862.2018.1440164

Ejemplares similares

Potent neutralizing anti-CD1d antibody reduces lung cytokine release in primate asthma model
por: Nambiar, Jonathan, et al.
Publicado: (2015)

Higher Binding Affinity and In Vitro Potency of Reslizumab for Interleukin-5 Compared With Mepolizumab
por: Liddament, Mark, et al.
Publicado: (2018)

Thymus-leukemia (TL) antigens of the mouse. Analysis of TL mRNA and TL cDNA TL+ and TL- strains
Publicado: (1985)

Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease
por: Richard, Arianne C., et al.
Publicado: (2018)

ANTIGENIC MODULATION : LOSS OF TL ANTIGEN FROM CELLS EXPOSED TO TL ANTIBODY. STUDY OF THE PHENOMENON IN VITRO
por: Old, Lloyd J., et al.
Publicado: (1968)

PRODUCTION OF TL ANTIBODY BY MICE IMMUNIZED WITH TL(-) CELL POPULATIONS : A POSSIBLE ASSAY FOR THYMIC HORMONE
por: Komuro, Katsutoshi, et al.
Publicado: (1973)

The TL1A-DR3 Axis in Asthma: Membrane-Bound and Secreted TL1A Co-Determined the Development of Airway Remodeling
por: Zhang, Jintao, et al.
Publicado: (2022)

TL antigen as a transplantation antigen recognized by TL-restricted cytotoxic T cells
Publicado: (1994)

Emergence of topological and topological crystalline phases in TlBiS(2) and TlSbS(2)
por: Zhang, Qingyun, et al.
Publicado: (2015)

Identification and decay of $^{182}$Tl
por: Bouldjedri, A, et al.
Publicado: (1991)

Coordination of Pnictogenylboranes Towards Tl(I) Salts and a Tl‐ Mediated P−P Coupling
por: Szlosek, Robert, et al.
Publicado: (2022)

ANTIGENIC MODULATION IN VITRO : I. Fate of Thymus-Leukemia (TL) Antigen-Antibody Complexes Following Modulation of TL Antigenicity from the Surfaces of Mouse Leukemia Cells and Thymocytes
por: Stackpole, Christopher W., et al.
Publicado: (1974)

Neutron capture measurement at the n TOF facility of the $^{204}$Tl and $^{205}$Tl s-process branching points
por: Casanovas, A, et al.
Publicado: (2020)

The applications of TL materials in neutron dosimetry
por: Douglas, J A
Publicado: (1978)

Nuclear magnetic moment of $^{207}$Tl
por: Neugart, R, et al.
Publicado: (1985)

$β$-delayed fission of $^{180}$Tl
por: Elseviers, J, et al.
Publicado: (2013)

Results of the Saclay NaI(Tl) WIMP search experiment and comparison with other NaI(Tl) experiments
por: Gerbier, G, et al.
Publicado: (2000)

A modified method of separating Tl(I) and Tl(III) in aqueous samples using solid phase extraction
por: Xiao, Qingxiang, et al.
Publicado: (2018)

Neutron capture cross section measurement of the heaviest s-process branching $^{204}$Tl and of $^{203}$Tl at CERN n_TOF
por: Casanovas Hoste, Adria
Publicado: (2020)

Electron capture delayed fission of $^{180}$Tl
por: Elseviers, Jytte
Publicado: (2013)

Tl(2)Mo(9)Se(11)
por: Gougeon, Patrick, et al.
Publicado: (2010)

On the scintillation response of NaI(Tl)-Crystals
por: Leutz, H, et al.
Publicado: (1996)

Decay study of $^{200}$Fr and $^{182}$Tl
por: Keupers, Marijke
Publicado: (2012)

Nuclear spectroscopy of some light Tl isotopes
por: Fényes, T, et al.
Publicado: (1970)

$\alpha$-decay study of $^{182,184}$Tl
por: Van Beveren, C, et al.
Publicado: (2016)

IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
por: Michelsen, Kathrin S., et al.
Publicado: (2009)

The Role of TL1A and DR3 in Autoimmune and Inflammatory Diseases
por: Aiba, Yoshihiro, et al.
Publicado: (2013)

99391 A TL1 Team Approach: The Role of Parents in Physical Activity Engagement Among Adolescents with Comorbid Asthma and Obesity
por: Yourell, Jacqlyn, et al.
Publicado: (2021)

A calibration method for NaI(Tl)-detectors
por: Kristiansson, A, et al.
Publicado: (1986)

The decay $^{207}_{80}$Hg --> $^{207}_{81}$Tl
por: Jonson, B, et al.
Publicado: (1981)

Guide tl the Galleria Nazionale d'Arte Moderna

Detailed $\alpha$-decay study of $^{180}\mathrm{Tl}$
por: Andel, B, et al.
Publicado: (2017)

Decay studies of the long-lived states in $^{186}$Tl
por: Stryjczyk, M., et al.
Publicado: (2020)

Note D'Exploitation des Redresseurs TlB
por: Blanc, JL
Publicado: (1991)

214 A TL1 Team Approach: Physician Strategies to Promote Physical Activity Among Youth with Comorbid Asthma and Overweight/Obesity
por: Koskela-Staples, Natalie C., et al.
Publicado: (2022)

Antagonistic Effect of Trichoderma longibrachiatum (TL6 and TL13) on Fusarium solani and Fusarium avenaceum Causing Root Rot on Snow Pea Plants
por: Boakye, Thomas Afriyie, et al.
Publicado: (2022)

Role of TL1A in Inflammatory Autoimmune Diseases: A Comprehensive Review
por: Xu, Wang-Dong, et al.
Publicado: (2022)

Asthma, atopy, antibiotics and the bowel.
por: Crane, J
Publicado: (2001)

Questions and answers on thermoluminescence (TL) and optically stimulated luminescence (OSL)
por: Furetta, Claudio
Publicado: (2008)

Shape coexistence in the lightest Tl isotopes studied by laser spectroscopy
por: Andreyev, A, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_33dslnqgmd6bt7p4o8oefngl31