Improved in vitro and in vivo activity against CD303-expressing targets of the chimeric 122A2 antibody selected for specific glycosylation pattern

Plasmacytoid dendritic cells (pDCs) play a central role for both innate and adaptive antiviral responses, as they direct immune responses through their unique ability to produce substantial concentrations of type I interferon (IFNs) upon viral encounter while also activating multiple immune cells, i...

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Detalles Bibliográficos
Autores principales: Fournier, Nathalie, Jacque, Emilie, Fontayne, Alexandre, Derache, Delphine, Dupont, Gilles, Verhaeghe, Lucie, Baptista, Linda, Dehenne, Aurélie, Dezetter, Anne-Sophie, Terrier, Aurélie, Longue, Alain, Pochet-Beghin, Virginie, Beghin, Cecile, Chtourou, Sami, de Romeuf, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973763/
https://www.ncbi.nlm.nih.gov/pubmed/29553870
http://dx.doi.org/10.1080/19420862.2018.1451283

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