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Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers

[Image: see text] Intriguingly, little is known about the impact of dispersity on the crystallization driven self-assembly (CDSA) of amphiphilic block copolymers in aqueous media. Here, we investigate the influence of dispersity on the CDSA of ABA-type amphiphilic block co-oligomers (ABCOs). Two pai...

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Autores principales: Das, Anindita, Petkau-Milroy, Katja, Klerks, Gilian, van Genabeek, Bas, Lafleur, René P. M., Palmans, Anja R. A., Meijer, E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973780/
https://www.ncbi.nlm.nih.gov/pubmed/29862138
http://dx.doi.org/10.1021/acsmacrolett.8b00168
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author Das, Anindita
Petkau-Milroy, Katja
Klerks, Gilian
van Genabeek, Bas
Lafleur, René P. M.
Palmans, Anja R. A.
Meijer, E. W.
author_facet Das, Anindita
Petkau-Milroy, Katja
Klerks, Gilian
van Genabeek, Bas
Lafleur, René P. M.
Palmans, Anja R. A.
Meijer, E. W.
author_sort Das, Anindita
collection PubMed
description [Image: see text] Intriguingly, little is known about the impact of dispersity on the crystallization driven self-assembly (CDSA) of amphiphilic block copolymers in aqueous media. Here, we investigate the influence of dispersity on the CDSA of ABA-type amphiphilic block co-oligomers (ABCOs). Two pairs of ABCOs are synthesized comprising discrete (Đ = 1.00) or disperse (Đ = 1.20) isotactic l-lactic acid 16-mers as the semicrystalline hydrophobic block and either oligo(ethylene glycol) methyl ether (MeOoEG) or oligo(tetraethylene glycol succinate) (oTEGSuc) as the discrete hydrophilic block. Self-assembly studies in water with 10% THF reveal uniform nanofibers/2D sheets for the discrete oligomers, but such structural regularity is largely compromised in the disperse oligomers. The results are corroborated by sharp melting transitions in both solution and bulk for the discrete ABCOs, unlike their disperse analogues that show a lack of crystallization. Interestingly, the discrete MeOoEG-LLA oligomer reveals crystallization driven gelation, illustrating the contrasting differences between the discrete oligomers and their disperse counterparts.
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spelling pubmed-59737802018-05-30 Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers Das, Anindita Petkau-Milroy, Katja Klerks, Gilian van Genabeek, Bas Lafleur, René P. M. Palmans, Anja R. A. Meijer, E. W. ACS Macro Lett [Image: see text] Intriguingly, little is known about the impact of dispersity on the crystallization driven self-assembly (CDSA) of amphiphilic block copolymers in aqueous media. Here, we investigate the influence of dispersity on the CDSA of ABA-type amphiphilic block co-oligomers (ABCOs). Two pairs of ABCOs are synthesized comprising discrete (Đ = 1.00) or disperse (Đ = 1.20) isotactic l-lactic acid 16-mers as the semicrystalline hydrophobic block and either oligo(ethylene glycol) methyl ether (MeOoEG) or oligo(tetraethylene glycol succinate) (oTEGSuc) as the discrete hydrophilic block. Self-assembly studies in water with 10% THF reveal uniform nanofibers/2D sheets for the discrete oligomers, but such structural regularity is largely compromised in the disperse oligomers. The results are corroborated by sharp melting transitions in both solution and bulk for the discrete ABCOs, unlike their disperse analogues that show a lack of crystallization. Interestingly, the discrete MeOoEG-LLA oligomer reveals crystallization driven gelation, illustrating the contrasting differences between the discrete oligomers and their disperse counterparts. American Chemical Society 2018-04-16 2018-05-15 /pmc/articles/PMC5973780/ /pubmed/29862138 http://dx.doi.org/10.1021/acsmacrolett.8b00168 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Das, Anindita
Petkau-Milroy, Katja
Klerks, Gilian
van Genabeek, Bas
Lafleur, René P. M.
Palmans, Anja R. A.
Meijer, E. W.
Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title_full Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title_fullStr Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title_full_unstemmed Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title_short Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers
title_sort consequences of dispersity on the self-assembly of aba-type amphiphilic block co-oligomers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973780/
https://www.ncbi.nlm.nih.gov/pubmed/29862138
http://dx.doi.org/10.1021/acsmacrolett.8b00168
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