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Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4(+) T cells
Human immunodeficiency virus (HIV) infection is currently incurable, due to the persistence of latently infected cells. The ‘shock and kill’ approach to a cure proposes to eliminate this reservoir via transcriptional activation of latent proviruses, enabling direct or indirect killing of infected ce...
Autores principales: | Battivelli, Emilie, Dahabieh, Matthew S, Abdel-Mohsen, Mohamed, Svensson, J Peter, Tojal Da Silva, Israel, Cohn, Lillian B, Gramatica, Andrea, Deeks, Steven, Greene, Warner C, Pillai, Satish K, Verdin, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973828/ https://www.ncbi.nlm.nih.gov/pubmed/29714165 http://dx.doi.org/10.7554/eLife.34655 |
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