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A population pharmacokinetic model of cabozantinib in healthy volunteers and patients with various cancer types
PURPOSE: An integrated population pharmacokinetic (popPK) model was developed to describe the pharmacokinetics (PK) of tyrosine kinase inhibitor cabozantinib in healthy volunteers (HVs) and patients with various cancer types and to identify any differences in cabozantinib PK across these populations...
Autores principales: | Lacy, Steven, Yang, Bei, Nielsen, Jace, Miles, Dale, Nguyen, Linh, Hutmacher, Matt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973963/ https://www.ncbi.nlm.nih.gov/pubmed/29687244 http://dx.doi.org/10.1007/s00280-018-3581-0 |
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