Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy

In liver cirrhosis (LC), impaired intestinal functions lead to dysbiosis and possible bacterial translocation (BT). Bacteria or their byproducts within the bloodstream can thus play a role in systemic inflammation and hepatic encephalopathy (HE). We combined 16S sequencing, NMR metabolomics and netw...

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Detalles Bibliográficos
Autores principales: Iebba, Valerio, Guerrieri, Francesca, Di Gregorio, Vincenza, Levrero, Massimo, Gagliardi, Antonella, Santangelo, Floriana, Sobolev, Anatoly P., Circi, Simone, Giannelli, Valerio, Mannina, Luisa, Schippa, Serena, Merli, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974022/
https://www.ncbi.nlm.nih.gov/pubmed/29844325
http://dx.doi.org/10.1038/s41598-018-26509-y

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