Cargando…

Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase

A novel synthesis of nucleotide sugars was conducted to prepare UDP-α-D-xylose and UDP-β-L-arabinose without utilizing protection strategies or advanced purification techniques. Sugar-1-phosphates of D-xylose and L-arabinose were synthesized from their β-glycosylsulfonylhydrazides and evaluated as s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, JiaJia, Greenway, Harmon, Li, Shanshan, Wei, Mohui, Polizzi, Samuel J., Wang, Peng G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974040/ https://www.ncbi.nlm.nih.gov/pubmed/29876343 http://dx.doi.org/10.3389/fchem.2018.00163

Ejemplares similares

Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase
por: Gu, Xiaogang, et al.
Publicado: (2011)

UDP-sugar pyrophosphorylase is essential for arabinose and xylose recycling, and is required during vegetative and reproductive growth in Arabidopsis
por: Geserick, Claudia, et al.
Publicado: (2013)

UDP-xylose and UDP-galactose synthesis in Trichomonas vaginalis
por: Rosenberger, Andrea F.N., et al.
Publicado: (2012)

UDP-sugar pyrophosphorylase controls the activity of proceeding sugar-1-kinases enzymes
por: Geserick, Claudia, et al.
Publicado: (2013)

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis
por: Damerow, Sebastian, et al.
Publicado: (2015)

Substrate Specificity and Inhibitor Sensitivity of Plant UDP-Sugar Producing Pyrophosphorylases
por: Decker, Daniel, et al.
Publicado: (2017)

The structure-activity relationship of the salicylimide derived inhibitors of UDP-sugar producing pyrophosphorylases
por: Decker, Daniel, et al.
Publicado: (2018)

Exploring Redox Modulation of Plant UDP-Glucose Pyrophosphorylase
por: Decker, Daniel, et al.
Publicado: (2023)

Three UDP-xylose transporters participate in xylan biosynthesis by conveying cytosolic UDP-xylose into the Golgi lumen in Arabidopsis
por: Zhao, Xianhai, et al.
Publicado: (2018)

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
por: Raimi, Olawale G., et al.
Publicado: (2020)

Mutagenesis of UDP‐xylose epimerase and xylan arabinosyl‐transferase decreases arabinose content and improves saccharification of rice straw
por: Chen, Chen, et al.
Publicado: (2021)

Effects of Magnesium, Pyrophosphate and Phosphonates on Pyrophosphorolytic Reaction of UDP-Glucose Pyrophosphorylase
por: Kleczkowski, Leszek A., et al.
Publicado: (2022)

Immobilization of the Highly Active UDP-Glucose Pyrophosphorylase From Thermocrispum agreste Provides a Highly Efficient Biocatalyst for the Production of UDP-Glucose
por: Kumpf, Antje, et al.
Publicado: (2020)

UDP-glucose pyrophosphorylase: genome-wide identification, expression and functional analyses in Gossypium hirsutum
por: Xu, Zhongyang, et al.
Publicado: (2022)

On the Ancestral UDP-Glucose Pyrophosphorylase Activity of GalF from Escherichia coli
por: Ebrecht, Ana C., et al.
Publicado: (2015)

Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane
por: Cotrim, Camila A., et al.
Publicado: (2018)

Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase
por: Zavala, Agustín, et al.
Publicado: (2017)

Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents
por: Yang, Yueqin, et al.
Publicado: (2020)

The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
por: Villafraz, Oriana, et al.
Publicado: (2021)

Structure and Mechanism of Human UDP-xylose Synthase: EVIDENCE FOR A PROMOTING ROLE OF SUGAR RING DISTORTION IN A THREE-STEP CATALYTIC CONVERSION OF UDP-GLUCURONIC ACID
por: Eixelsberger, Thomas, et al.
Publicado: (2012)

Cloning, Characterization, and RNA Interference Effect of the UDP-N-Acetylglucosamine Pyrophosphorylase Gene in Cnaphalocrocis medinalis
por: Zhou, Yuan-Jin, et al.
Publicado: (2021)

Isotope Probing of the UDP‐Apiose/UDP‐Xylose Synthase Reaction: Evidence of a Mechanism via a Coupled Oxidation and Aldol Cleavage
por: Eixelsberger, Thomas, et al.
Publicado: (2017)

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target
por: Fang, Wenxia, et al.
Publicado: (2013)

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening
por: Prakash, Ohm, et al.
Publicado: (2019)

Identification of UDP-rhamnosyltransferases and UDP-galactosyltransferase involved in flavonol glycosylation in Morella rubra
por: Ren, Chuanhong, et al.
Publicado: (2022)

UDP-Galactose 4′-Epimerase Activities toward UDP-Gal and UDP-GalNAc Play Different Roles in the Development of Drosophila melanogaster
por: Daenzer, Jennifer M. I., et al.
Publicado: (2012)

Molecular and Functional Analysis of UDP-N-Acetylglucosamine Pyrophosphorylases from the Migratory Locust, Locusta migratoria
por: Liu, Xiaojian, et al.
Publicado: (2013)

A Chimeric UDP-Glucose Pyrophosphorylase Produced by Protein Engineering Exhibits Sensitivity to Allosteric Regulators
por: Asención Diez, Matías D., et al.
Publicado: (2013)

Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase): in vitro validation of a putative inhibitor
por: Sharma, Monica, et al.
Publicado: (2020)

UDP-Sugar Producing Pyrophosphorylases: Distinct and Essential Enzymes With Overlapping Substrate Specificities, Providing de novo Precursors for Glycosylation Reactions
por: Decker, Daniel, et al.
Publicado: (2019)

Overexpression of UDP‐sugar pyrophosphorylase leads to higher sensitivity towards galactose, providing new insights into the mechanisms of galactose toxicity in plants
por: Althammer, Martina, et al.
Publicado: (2022)

Arabidopsis MAP-Kinase 3 Phosphorylates UDP-Glucose Dehydrogenase: a Key Enzyme Providing UDP-Sugar for Cell Wall Biosynthesis
por: Kohlberger, Michael, et al.
Publicado: (2018)

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth
por: Wolfe, Andrew L., et al.
Publicado: (2021)

UDP-glucose pyrophosphorylase as a target for regulating carbon flux distribution and antioxidant capacity in Phaeodactylum tricornutum
por: Zhang, Ruihao, et al.
Publicado: (2023)

Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations
por: Wagstaff, Ben A., et al.
Publicado: (2015)

UDP calzado, Acatlán, Veracruz
por: Ramírez Vázquez, Cindy Berenice
Publicado: (2014)

Global Analysis of UDP Glucose Pyrophosphorylase (UDPGP) Gene Family in Plants: Conserved Evolution Involved in Cell Death
por: Liu, Shuai, et al.
Publicado: (2021)

Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase
por: Mariño, Karina, et al.
Publicado: (2010)

Amelioration of cold-induced sweetening in potato by RNAi mediated silencing of StUGPase encoding UDP-glucose pyrophosphorylase
por: Jaiswal, Sandeep, et al.
Publicado: (2023)

Determination of UDP-Glucose and UDP-Galactose in Maize by Hydrophilic Interaction Liquid Chromatography and Tandem Mass Spectrometry
por: Lan, Chen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qlrt3sqnl5vd6s948b1oqdhi5a