Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency

Genome editing is the introduction of directed modifications in the genome, a process boosted to therapeutic levels by designer nucleases. Building on the experience of ex vivo gene therapy for severe combined immunodeficiencies, it is likely that genome editing of haematopoietic stem/progenitor cel...

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Detalles Bibliográficos
Autores principales: Abdul-Razak, H. H., Rocca, C. J., Howe, S. J., Alonso-Ferrero, M. E., Wang, J., Gabriel, R., Bartholomae, C. C., Gan, C. H. V., Garín, M. I., Roberts, A., Blundell, M. P., Prakash, V., Molina-Estevez, F. J., Pantoglou, J., Guenechea, G., Holmes, M. C., Gregory, P. D., Kinnon, C., von Kalle, C., Schmidt, M., Bueren, J. A., Thrasher, A. J., Yáñez-Muñoz, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974076/
https://www.ncbi.nlm.nih.gov/pubmed/29844458
http://dx.doi.org/10.1038/s41598-018-26439-9

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