Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

Mounting an effective immune response against cancer requires the activation of innate and adaptive immune cells. Metastatic melanoma is the most aggressive form of skin cancer. While immunotherapies have shown a remarkable success in melanoma treatment, patients develop resistance by mechanisms tha...

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Detalles Bibliográficos
Autores principales: Figueiredo, Carlos R., Azevedo, Ricardo A., Mousdell, Sasha, Resende-Lara, Pedro T., Ireland, Lucy, Santos, Almudena, Girola, Natalia, Cunha, Rodrigo L. O. R., Schmid, Michael C., Polonelli, Luciano, Travassos, Luiz R., Mielgo, Ainhoa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974174/
https://www.ncbi.nlm.nih.gov/pubmed/29875777
http://dx.doi.org/10.3389/fimmu.2018.01132

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