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Increased H3K27ac level of ACE mediates the intergenerational effect of low peak bone mass induced by prenatal dexamethasone exposure in male offspring rats

Prenatal dexamethasone exposure (PDE) induces developmental toxicities of multiple organs in offspring. Here, we verified the intergenerational effect of low peak bone mass induced by PDE and investigated its intrauterine programming mechanism. Pregnant rats were injected subcutaneously with 0.2 mg/...

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Detalles Bibliográficos
Autores principales:	Xiao, Hao, Wen, Yinxian, Pan, Zhengqi, Shangguan, Yangfan, Qin, Jun, Tan, Yang, Jiang, Hongqiang, Li, Bin, Zhang, Qi, Chen, Liaobin, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974192/ https://www.ncbi.nlm.nih.gov/pubmed/29844424 http://dx.doi.org/10.1038/s41419-018-0701-z

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