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Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system
Despite decades of investigation on the proliferation of adult human primary hepatocytes, their expansion in vitro still remains challenging. To later be able to consider hepatocytes as a cell therapy alternative or bridge to liver transplantation, dramatically impeded by a shortage in liver donors,...
Autores principales: | Garnier, Delphine, Li, Ruoya, Delbos, Frédéric, Fourrier, Angélique, Collet, Camille, Guguen-Guillouzo, Christiane, Chesné, Christophe, Nguyen, Tuan Huy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974235/ https://www.ncbi.nlm.nih.gov/pubmed/29844473 http://dx.doi.org/10.1038/s41598-018-26584-1 |
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