Cargando…
Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma
Neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia, and glaucoma, affect millions of people worldwide. ALS is caused by the loss of motor neurons in the spinal cord, brainstem, and brain, and genetic mutations are responsible for 10% of all ALS cases....
Autores principales: | Toth, Reka P., Atkin, Julie D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974248/ https://www.ncbi.nlm.nih.gov/pubmed/29875767 http://dx.doi.org/10.3389/fimmu.2018.01017 |
Ejemplares similares
-
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
por: Nakazawa, Seshiru, et al.
Publicado: (2016) -
Altered Functions and Interactions of Glaucoma-Associated Mutants of Optineurin
por: Swarup, Ghanshyam, et al.
Publicado: (2018) -
Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis
por: Dominguez, Jacqueline, et al.
Publicado: (2021) -
Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum
por: Shahheydari, Hamideh, et al.
Publicado: (2017) -
Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer
por: Weil, Robert, et al.
Publicado: (2018)