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Induction of anergic or regulatory tumor-specific CD4(+) T cells in the tumor-draining lymph node

CD4(+) T cell antitumor responses have mostly been studied in transplanted tumors expressing secreted model antigens (Ags), while most mutated proteins in human cancers are not secreted. The fate of Ag-specific CD4(+) T cells recognizing a cytoplasmic Ag in mice bearing autochthonous tumors is still...

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Detalles Bibliográficos
Autores principales:	Alonso, Ruby, Flament, Héloïse, Lemoine, Sébastien, Sedlik, Christine, Bottasso, Emanuel, Péguillet, Isabel, Prémel, Virginie, Denizeau, Jordan, Salou, Marion, Darbois, Aurélie, Núñez, Nicolás Gonzalo, Salomon, Benoit, Gross, David, Piaggio, Eliane, Lantz, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974295/ https://www.ncbi.nlm.nih.gov/pubmed/29844317 http://dx.doi.org/10.1038/s41467-018-04524-x

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