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STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap

The perinuclear actin cap is an important cytoskeletal structure that regulates nuclear morphology and re-orientation during front-rear polarisation. The mechanisms regulating the actin cap are currently poorly understood. Here, we demonstrate that STEF/TIAM2, a Rac1 selective guanine nucleotide exc...

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Detalles Bibliográficos
Autores principales:	Woroniuk, Anna, Porter, Andrew, White, Gavin, Newman, Daniel T., Diamantopoulou, Zoi, Waring, Thomas, Rooney, Claire, Strathdee, Douglas, Marston, Daniel J., Hahn, Klaus M., Sansom, Owen J., Zech, Tobias, Malliri, Angeliki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974301/ https://www.ncbi.nlm.nih.gov/pubmed/29844364 http://dx.doi.org/10.1038/s41467-018-04404-4

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