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Import and Export of Misfolded α-Synuclein

In Parkinson's disease, intracellular α-synuclein (α-syn) inclusions form in neurons and are referred to as Lewy bodies. These aggregates spread through the brain following a specific pattern leading to the hypothesis that neuron-to-neuron transfer is critical for the propagation of Lewy body p...

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Detalles Bibliográficos
Autores principales: Rodriguez, Lilia, Marano, Maria M., Tandon, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974333/
https://www.ncbi.nlm.nih.gov/pubmed/29875627
http://dx.doi.org/10.3389/fnins.2018.00344

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