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Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a

Disruption of the blood-brain barrier (BBB) by cancer cells is linked to metastatic tumor initiation and progression; however, the pathways that drive these events remain poorly understood. Here, we have developed novel patient-derived xenograft (PDX) models of brain metastases that recapitulate pat...

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Detalles Bibliográficos
Autores principales:	Tiwary, Shweta, Morales, John E., Kwiatkowski, Sam C., Lang, Frederick F., Rao, Ganesh, McCarty, Joseph H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974340/ https://www.ncbi.nlm.nih.gov/pubmed/29844613 http://dx.doi.org/10.1038/s41598-018-26636-6

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