Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic

Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU), a WHO-defined neglected tropical disease. All Japanese BU causative isolates have shown distinct differences from the prototype and are categorized as M. ulcerans subspecies shinshuense. During repeated sub-culture, we found that so...

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Detalles Bibliográficos
Autores principales: Nakanaga, Kazue, Ogura, Yoshitoshi, Toyoda, Atsushi, Yoshida, Mitsunori, Fukano, Hanako, Fujiwara, Nagatoshi, Miyamoto, Yuji, Nakata, Noboru, Kazumi, Yuko, Maeda, Shinji, Ooka, Tadasuke, Goto, Masamichi, Tanigawa, Kazunari, Mitarai, Satoshi, Suzuki, Koichi, Ishii, Norihisa, Ato, Manabu, Hayashi, Tetsuya, Hoshino, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974349/
https://www.ncbi.nlm.nih.gov/pubmed/29844323
http://dx.doi.org/10.1038/s41598-018-26425-1

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