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The hedgehog and Wnt/β-catenin system machinery mediate myofibroblast differentiation of LR-MSCs in pulmonary fibrogenesis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal lung disease that is characterized by enhanced changes in stem cell differentiation and fibroblast proliferation. Resident mesenchymal stem cells (LR-MSCs) can undergo phenotype conversion to myofibroblasts to augment extracellu...

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Detalles Bibliográficos
Autores principales:	Chen, Xiang, Shi, Chaowen, Cao, Honghui, Chen, Ling, Hou, Jiwei, Xiang, Zou, Hu, Kebin, Han, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974360/ https://www.ncbi.nlm.nih.gov/pubmed/29844390 http://dx.doi.org/10.1038/s41419-018-0692-9

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