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Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids
Rotavirus (RV) primarily infects enterocytes and results in severe diarrhea, particularly in children. It is known that the host immune responses determine the outcome of viral infections. Following infections, interferons (IFNs) are produced as the first and the main anti-viral cytokines to combat...
Autores principales: | Hakim, Mohamad S., Chen, Sunrui, Ding, Shihao, Yin, Yuebang, Ikram, Aqsa, Ma, Xiao-xia, Wang, Wenshi, Peppelenbosch, Maikel P., Pan, Qiuwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974418/ https://www.ncbi.nlm.nih.gov/pubmed/29844362 http://dx.doi.org/10.1038/s41598-018-26784-9 |
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