Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China

Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an...

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Detalles Bibliográficos
Autores principales: Shen, Hanqin, Liu, Xiangcong, Zhang, Pengfei, Wang, Lei, Liu, Yanling, Zhang, Leyi, Liang, Pengshuai, Song, Changxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974529/
https://www.ncbi.nlm.nih.gov/pubmed/29284212
http://dx.doi.org/10.4142/jvs.2018.19.3.468
Descripción
Sumario:Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles < 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV.

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