Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China

Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an...

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Autores principales: Shen, Hanqin, Liu, Xiangcong, Zhang, Pengfei, Wang, Lei, Liu, Yanling, Zhang, Leyi, Liang, Pengshuai, Song, Changxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974529/
https://www.ncbi.nlm.nih.gov/pubmed/29284212
http://dx.doi.org/10.4142/jvs.2018.19.3.468
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author Shen, Hanqin
Liu, Xiangcong
Zhang, Pengfei
Wang, Lei
Liu, Yanling
Zhang, Leyi
Liang, Pengshuai
Song, Changxu
author_facet Shen, Hanqin
Liu, Xiangcong
Zhang, Pengfei
Wang, Lei
Liu, Yanling
Zhang, Leyi
Liang, Pengshuai
Song, Changxu
author_sort Shen, Hanqin
collection PubMed
description Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles < 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV.
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spelling pubmed-59745292018-05-31 Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China Shen, Hanqin Liu, Xiangcong Zhang, Pengfei Wang, Lei Liu, Yanling Zhang, Leyi Liang, Pengshuai Song, Changxu J Vet Sci Short Communication Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles < 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV. The Korean Society of Veterinary Science 2018-05 2018-05-28 /pmc/articles/PMC5974529/ /pubmed/29284212 http://dx.doi.org/10.4142/jvs.2018.19.3.468 Text en © 2018 The Korean Society of Veterinary Science http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Shen, Hanqin
Liu, Xiangcong
Zhang, Pengfei
Wang, Lei
Liu, Yanling
Zhang, Leyi
Liang, Pengshuai
Song, Changxu
Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title_full Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title_fullStr Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title_full_unstemmed Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title_short Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
title_sort identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in china
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974529/
https://www.ncbi.nlm.nih.gov/pubmed/29284212
http://dx.doi.org/10.4142/jvs.2018.19.3.468
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