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Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift
Stem cells are considered the origin of neoplasms in general, and malignant tumours in particular, and the stage at which the stem cells stop their differentiation determines the degree of malignancy. However, there is increasing evidence supporting an alternative paradigm. Tumours may develop by de...
Autores principales: | Waldum, Helge L., Öberg, Kjell, Sørdal, Øystein F., Sandvik, Arne K., Gustafsson, Bjørn I., Mjønes, Patricia, Fossmark, Reidar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974566/ https://www.ncbi.nlm.nih.gov/pubmed/29872453 http://dx.doi.org/10.1177/1756284818775054 |
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