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Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai

Background: Mumbai is witnessing a rising incidence of all forms of drug resistant tuberculosis (DR-TB). Methods: A population-based, retrospective study was conducted between April and July 2014, in 15 high TB burden wards in Mumbai, to capture the patient pathways to TB care. A total of 23 DR-TB p...

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Autores principales: Lobo, Eunice, Shah, Shimoni, Rangan, Sheela, Dholakia, Yatin, Mistry, Nerges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974602/
https://www.ncbi.nlm.nih.gov/pubmed/29863175
http://dx.doi.org/10.12688/gatesopenres.12785.2
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author Lobo, Eunice
Shah, Shimoni
Rangan, Sheela
Dholakia, Yatin
Mistry, Nerges
author_facet Lobo, Eunice
Shah, Shimoni
Rangan, Sheela
Dholakia, Yatin
Mistry, Nerges
author_sort Lobo, Eunice
collection PubMed
description Background: Mumbai is witnessing a rising incidence of all forms of drug resistant tuberculosis (DR-TB). Methods: A population-based, retrospective study was conducted between April and July 2014, in 15 high TB burden wards in Mumbai, to capture the patient pathways to TB care. A total of 23 DR-TB patients were identified and their pathways to access DR-TB care were recorded using semi-structured interviews. Results: The total DR-TB pathway time of new patients (who did not report any past episode of TB) (180 days; IQR 123,346) was found to be more than twice that of retreatment patients (who reported a past episode of TB) (69 days; IQR 42,128). Conclusions: The unacceptable delay for diagnosis and treatment of DR-TB in Mumbai advocates for consistent implementation of early screening of patients using rapid gene-based technologies.
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spelling pubmed-59746022018-05-30 Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai Lobo, Eunice Shah, Shimoni Rangan, Sheela Dholakia, Yatin Mistry, Nerges Gates Open Res Research Article Background: Mumbai is witnessing a rising incidence of all forms of drug resistant tuberculosis (DR-TB). Methods: A population-based, retrospective study was conducted between April and July 2014, in 15 high TB burden wards in Mumbai, to capture the patient pathways to TB care. A total of 23 DR-TB patients were identified and their pathways to access DR-TB care were recorded using semi-structured interviews. Results: The total DR-TB pathway time of new patients (who did not report any past episode of TB) (180 days; IQR 123,346) was found to be more than twice that of retreatment patients (who reported a past episode of TB) (69 days; IQR 42,128). Conclusions: The unacceptable delay for diagnosis and treatment of DR-TB in Mumbai advocates for consistent implementation of early screening of patients using rapid gene-based technologies. F1000 Research Limited 2018-05-10 /pmc/articles/PMC5974602/ /pubmed/29863175 http://dx.doi.org/10.12688/gatesopenres.12785.2 Text en Copyright: © 2018 Lobo E et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lobo, Eunice
Shah, Shimoni
Rangan, Sheela
Dholakia, Yatin
Mistry, Nerges
Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title_full Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title_fullStr Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title_full_unstemmed Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title_short Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
title_sort pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high tb burden wards in mumbai
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974602/
https://www.ncbi.nlm.nih.gov/pubmed/29863175
http://dx.doi.org/10.12688/gatesopenres.12785.2
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