Cargando…

Actin Dysfunction Induces Cell Cycle Delay at G2/M with Sustained ERK and RSK Activation in IMR-90 Normal Human Fibroblasts

The actin cytoskeleton plays a key role in the entry of mitosis as well as in cytokinesis. In a previous study, we showed that actin disruption delays mitotic entry at G2/M by sustained activation of extracellular signal-related kinase 1/2 (ERK1/2) in primary cells but not in transformed cancer cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrestha, Deepmala, Choi, Daeun, Song, Kiwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974620/
https://www.ncbi.nlm.nih.gov/pubmed/29754473
http://dx.doi.org/10.14348/molcells.2018.2266