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Presence and leaching of bisphenol a (BPA) from dental materials

BPA has been reported to leach from some resin based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, we have investigated the leaching of...

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Autores principales: Becher, Rune, Wellendorf, Hanne, Sakhi, Amrit Kaur, Samuelsen, Jan Tore, Thomsen, Cathrine, Bølling, Anette Kocbach, Kopperud, Hilde Molvig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974758/
https://www.ncbi.nlm.nih.gov/pubmed/29868625
http://dx.doi.org/10.1080/23337931.2018.1476869
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author Becher, Rune
Wellendorf, Hanne
Sakhi, Amrit Kaur
Samuelsen, Jan Tore
Thomsen, Cathrine
Bølling, Anette Kocbach
Kopperud, Hilde Molvig
author_facet Becher, Rune
Wellendorf, Hanne
Sakhi, Amrit Kaur
Samuelsen, Jan Tore
Thomsen, Cathrine
Bølling, Anette Kocbach
Kopperud, Hilde Molvig
author_sort Becher, Rune
collection PubMed
description BPA has been reported to leach from some resin based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, we have investigated the leaching of BPA from 4 composite filling materials, 3 sealants and 2 orthodontic bonding materials. The materials were either uncured and dissolved in methanol or cured. The cured materials were kept in deionized water for 24 hours or 2 weeks. Samples were subsequently analyzed by ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS-MS). The composite filling material Tetric EvoFlow(®) and the fissure sealant DELTON(®) showed significantly higher levels of BPA leaching compared to control samples for all test conditions (uncured, 24 h leaching and 2 weeks leaching). There were no significant differences in amount of leached BPA for any of the tested materials after 24 hours compared to 2 weeks. These results show that BPA is still released from some dental materials despite the general concern about potential adverse effects of BPA. However, the amounts of BPA were relatively low and most likely represent a very small contribution to the total BPA exposure.
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spelling pubmed-59747582018-06-04 Presence and leaching of bisphenol a (BPA) from dental materials Becher, Rune Wellendorf, Hanne Sakhi, Amrit Kaur Samuelsen, Jan Tore Thomsen, Cathrine Bølling, Anette Kocbach Kopperud, Hilde Molvig Acta Biomater Odontol Scand Original Article BPA has been reported to leach from some resin based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, we have investigated the leaching of BPA from 4 composite filling materials, 3 sealants and 2 orthodontic bonding materials. The materials were either uncured and dissolved in methanol or cured. The cured materials were kept in deionized water for 24 hours or 2 weeks. Samples were subsequently analyzed by ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS-MS). The composite filling material Tetric EvoFlow(®) and the fissure sealant DELTON(®) showed significantly higher levels of BPA leaching compared to control samples for all test conditions (uncured, 24 h leaching and 2 weeks leaching). There were no significant differences in amount of leached BPA for any of the tested materials after 24 hours compared to 2 weeks. These results show that BPA is still released from some dental materials despite the general concern about potential adverse effects of BPA. However, the amounts of BPA were relatively low and most likely represent a very small contribution to the total BPA exposure. Taylor & Francis 2018-05-27 /pmc/articles/PMC5974758/ /pubmed/29868625 http://dx.doi.org/10.1080/23337931.2018.1476869 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Becher, Rune
Wellendorf, Hanne
Sakhi, Amrit Kaur
Samuelsen, Jan Tore
Thomsen, Cathrine
Bølling, Anette Kocbach
Kopperud, Hilde Molvig
Presence and leaching of bisphenol a (BPA) from dental materials
title Presence and leaching of bisphenol a (BPA) from dental materials
title_full Presence and leaching of bisphenol a (BPA) from dental materials
title_fullStr Presence and leaching of bisphenol a (BPA) from dental materials
title_full_unstemmed Presence and leaching of bisphenol a (BPA) from dental materials
title_short Presence and leaching of bisphenol a (BPA) from dental materials
title_sort presence and leaching of bisphenol a (bpa) from dental materials
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974758/
https://www.ncbi.nlm.nih.gov/pubmed/29868625
http://dx.doi.org/10.1080/23337931.2018.1476869
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