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Targets Fishing and Identification of Calenduloside E as Hsp90AB1: Design, Synthesis, and Evaluation of Clickable Activity-Based Probe

Calenduloside E (CE), a natural triterpenoid compound isolated from Aralia elata, can protect against ox-LDL-induced human umbilical vein endothelial cell (HUVEC) injury in our previous reports. However, the exact targets and mechanisms of CE remain elusive. For the sake of resolving this question,...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Tian, Yu, Zhang, Jing-Yi, Xu, Hui-Bo, Zhou, Ping, Wang, Min, Lu, Sen-Bao, Luo, Yun, Sun, Gui-Bo, Xu, Xu-Dong, Sun, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974765/
https://www.ncbi.nlm.nih.gov/pubmed/29875664
http://dx.doi.org/10.3389/fphar.2018.00532