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Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis

We review key morphogenetic events that occur during Caenorhabditis elegans (www.wormbase.org/) embryogenesis. Morphogenesis transforms tissues from one shape into another through cell migrations and shape changes, often utilizing highly conserved actin-based contractile systems. Three major morphog...

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Detalles Bibliográficos
Autores principales: Piekny, A. J., Mains, P. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974773/
https://www.ncbi.nlm.nih.gov/pubmed/14755119
http://dx.doi.org/10.1100/tsw.2003.123
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author Piekny, A. J.
Mains, P. E.
author_facet Piekny, A. J.
Mains, P. E.
author_sort Piekny, A. J.
collection PubMed
description We review key morphogenetic events that occur during Caenorhabditis elegans (www.wormbase.org/) embryogenesis. Morphogenesis transforms tissues from one shape into another through cell migrations and shape changes, often utilizing highly conserved actin-based contractile systems. Three major morphogenetic events occur during C. elegans embryogenesis: (1) dorsal intercalation, during which two rows of dorsal epidermal cells intercalate to form a single row; (2) ventral enclosure, where the dorsally located sheet of epidermal cells stretches to the ventral midline, encasing the embryo within a single epithelial sheet; and (3) elongation, during which actin-mediated contractions within the epithelial sheet lengthens the embryo. Here, we describe the known molecular players involved in each of these processes.
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spelling pubmed-59747732018-06-10 Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis Piekny, A. J. Mains, P. E. ScientificWorldJournal Mini-Review Article We review key morphogenetic events that occur during Caenorhabditis elegans (www.wormbase.org/) embryogenesis. Morphogenesis transforms tissues from one shape into another through cell migrations and shape changes, often utilizing highly conserved actin-based contractile systems. Three major morphogenetic events occur during C. elegans embryogenesis: (1) dorsal intercalation, during which two rows of dorsal epidermal cells intercalate to form a single row; (2) ventral enclosure, where the dorsally located sheet of epidermal cells stretches to the ventral midline, encasing the embryo within a single epithelial sheet; and (3) elongation, during which actin-mediated contractions within the epithelial sheet lengthens the embryo. Here, we describe the known molecular players involved in each of these processes. TheScientificWorldJOURNAL 2003-12-18 /pmc/articles/PMC5974773/ /pubmed/14755119 http://dx.doi.org/10.1100/tsw.2003.123 Text en Copyright © 2003 A. J. Piekny and P. E. Mains. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mini-Review Article
Piekny, A. J.
Mains, P. E.
Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title_full Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title_fullStr Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title_full_unstemmed Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title_short Squeezing an Egg into a Worm: C. elegans Embryonic Morphogenesis
title_sort squeezing an egg into a worm: c. elegans embryonic morphogenesis
topic Mini-Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974773/
https://www.ncbi.nlm.nih.gov/pubmed/14755119
http://dx.doi.org/10.1100/tsw.2003.123
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