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Synthesis of Platinum Complexes from N-Benzyl-2-Aminoethanethiol Derivatives

Twelve new platinum(II) complexes, analogs of cisplatin, containing a 2-aminoethanethiol N-substituted by several benzyl groups have been prepared and characterized in good yields. The ligands were obtained by reaction between 2-aminoethanethiol hydrochloride and different benzyl halides

Detalles Bibliográficos
Autores principales: de Almeida, Mauro Vieira, de Oliviera, Laura Lúcia C., Cesar, Eloi Teixeira, de Souza, Marcus Vinícius N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974807/
https://www.ncbi.nlm.nih.gov/pubmed/12806099
http://dx.doi.org/10.1100/tsw.2003.31
Descripción
Sumario:Twelve new platinum(II) complexes, analogs of cisplatin, containing a 2-aminoethanethiol N-substituted by several benzyl groups have been prepared and characterized in good yields. The ligands were obtained by reaction between 2-aminoethanethiol hydrochloride and different benzyl halides