A Role for Exocytosis in the Spatial Regulationof Actin Organization

The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role i...

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Detalles Bibliográficos
Autores principales: Gao, Xiang-Dong, Albert, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2003
Materias:
Directions in Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974875/
https://www.ncbi.nlm.nih.gov/pubmed/14755117
http://dx.doi.org/10.1100/tsw.2003.119
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author Gao, Xiang-Dong
Albert, Stefan
author_facet Gao, Xiang-Dong
Albert, Stefan
author_sort Gao, Xiang-Dong
collection PubMed
description The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other.
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spelling pubmed-59748752018-06-10 A Role for Exocytosis in the Spatial Regulationof Actin Organization Gao, Xiang-Dong Albert, Stefan ScientificWorldJournal Directions in Science The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood. By using yeast mutants defective in actin organization and secretion, we demonstrated that exocytosis plays a role in the spatial regulation of actin organization. Our findings suggest that the actin cytoskeleton, exocytosis, and perhaps endocytosis, may depend on each other for efficiency and reinforce each other. TheScientificWorldJOURNAL 2003-12-18 /pmc/articles/PMC5974875/ /pubmed/14755117 http://dx.doi.org/10.1100/tsw.2003.119 Text en Copyright © 2003 Xiang-Dong Gao and Stefan Albert. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Directions in Science
Gao, Xiang-Dong
Albert, Stefan
A Role for Exocytosis in the Spatial Regulationof Actin Organization
title A Role for Exocytosis in the Spatial Regulationof Actin Organization
title_full A Role for Exocytosis in the Spatial Regulationof Actin Organization
title_fullStr A Role for Exocytosis in the Spatial Regulationof Actin Organization
title_full_unstemmed A Role for Exocytosis in the Spatial Regulationof Actin Organization
title_short A Role for Exocytosis in the Spatial Regulationof Actin Organization
title_sort role for exocytosis in the spatial regulationof actin organization
topic Directions in Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974875/
https://www.ncbi.nlm.nih.gov/pubmed/14755117
http://dx.doi.org/10.1100/tsw.2003.119
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